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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Neurobiol Aging. 2014 May 27;35(11):2458–2464. doi: 10.1016/j.neurobiolaging.2014.05.016

Figure 6. The effect of Zileuton on synaptic integrity and neuroinflammation in aged 3xTg mice.

Figure 6

A. Representative Western blot analyses of synaptophysin (SYP) and post-synaptic protein-95 (PSD-95) in brain homogenates of 15 months old 3xTg mice receiving placebo (CTR) or zileuton (ZIL). B. Densitometric analyses of the immunoreactivities shown in the previous panel. (*p<0.05). C. Representative Western blot analyses of glial fibrillary acidic protein (GFAP) and ionized calcium-binding adapter molecule 1 (IBA-1) in brain homogenates of 15 months old 3xTg mice receiving placebo (CTR) or zileuton (ZIL). D. Densitometric analyses of the immunoreactivities shown in the previous panel. (*p<0.05). Results are mean ± sem.