Table 1.
Partial list of reported miR-22 target genes.
Target genes | Tissue or cell content | References |
---|---|---|
Sirt1 | Heart, Cancer cell | [18], [25], [43] |
HDAC4 | Heart, Cancer cell, Neuron | [18], [44], [45] |
PPARα | Heart, Chondrocyte | [18], [25], [46] |
PGC1-α | Heart | [25] |
PurB | Heart | [20] |
BMP7 | Chondrocyte, Kidney | [46], [47] |
ER-alpha | Cancer cell | [48] |
pTEN | Cardiomyocyte, Cancer cell line | [49], [22] |
MAX | Cancer cell | [50] |
EVI-1 | Cancer cell | [51] |
CDK6 | Cancer cell | [43] |
Sp1 | Cancer cell | [43] |
P21 | Cancer cell | [52] |
HIF-1α | Cancer cell | [53] |
HDAC6 | Human adipose tissue-derived mesenchymal stem cells | [54] |
ErbB3 | Cancer cell | [34] |
OGN | Cardiac fibroblast | [55] |
Irf8 | Dendritic cell | [56] |
Rcor1 | Neuron | [45] |
Rgs2 | Neuron | [45] |
YWHAZ | Dendritic cell | [57] |
TET2 | Cancer cell, hematopoietic stem cell | [29], [28] |