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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Magn Reson Imaging. 2014 Aug 2;32(9):1067–1077. doi: 10.1016/j.mri.2014.07.010

Fig. 2.

Fig. 2

Functional T1ρ mapping time series processing methods. With standard processing (Method 1), T1ρ and S0 maps are calculated using every pair of 10 and 50 ms TSL images (dashed boxes), yielding a frame time of 4.0 sec. With temporal interpolation (Methods 2 and 3), either subsequent 10 ms (Method 2) or 50 ms (Method 3) TSL images are averaged to generate an estimate at the same time as the paired TSL image. This technique also has a 4.0 sec frame time but may provide a better estimate of T1ρ at each time point as well as decrease sensitivity to between-TSL changes in T1 and S0. With sliding window (Method 4), maps are calculated with every new TSL image, yielding a 2.0 sec frame time. Method 5 combines sliding window and temporal interpolation.