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Description of LU states
| LU State | Distinguishing Characteristics | Relevant Pathology Score (PS) |
|---|---|---|
| Healthy (H) | Normal liver function, homeostatic levels of IL-6 and IL-6r | 1 |
| Compromised (C) | Intermediate state, events initiate inflammatory pathways which are normally countered by IL-6 signaling. | 2 |
| Inflamed (I) | Contains markers for the early stages of auto-immune hepatitis, including inflammation and lymphoplasmacytic portal infiltration | 4 |
