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Sensitivity of HepG2 cells to adriamycin determined by the MTT assay. After the treatment with 0.15625, 0.31250, 0.62500, 1.25000, 2.50000 × 10-3 g/L adriamycin for 48 h, the cells in-three dimensional cell culture and monolayer culture were cultured with MTT solution and cell inhibition ratio was determined. The cells in monolayer culture were more sensitive to adriamycin (P < 0.01).
