Table 2.
Genotype at NOD2 polymorphisms in CD cases and healthy controls
| Mutation | Group |
Genotype count, n (%) |
OR (95% CI)1 | P2 | ||
| WT/WT | Heterozygous | Homozygous | ||||
| R702W | CD | 75 (77.32) | 21 (21.65) | 1 (1.03) | 7.04 (1.58-31.30) | 0.004 |
| Controls | 48 (96.00) | 2 (4.00) | 0 | |||
| G908R | CD | 92 (94.85) | 5 (5.15) | 0 | 0.166 | |
| Controls | 50 (100) | 0 | 0 | |||
| L1007finsC | CD | 89 (91.75) | 8 (8.25) | 0 | 4.40 (0.53-36.25) | 0.167 |
| Controls | 49 (98.00) | 1 (2.00) | 0 | |||
1
ORs and probability values for disease status associated with carriage of at least 1 mutant allele (heterozygous, compound heterozygous and homozygous were grouped together). 2P-values were calculated with the Fisher's Exact test when comparing controls and CD patients.