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. 2007 Oct 21;13(39):5196–5207. doi: 10.3748/wjg.v13.i39.5196

Table 3.

Antioxidant/antioxidant enzymes and TBARS levels in swim stress induced ulcer model (n = 6) mean ± SD

Parameters Protein (mg/g) SOD (U/mg) Catalase (U/mg) Glutathione Peroxidase (ηmoles/g) GSH (nmoles/mg) TBARS ηmoles
Stomach
Healthy 2.23c ± 0.21 9.86a ± 1.1 829.2c ± 41.6 0.21a ± 0.009 224c ± 10.0 0.31a ± 0.01
Ulcerated 1.95a ± 0.13 19.10c ± 1.8 462.4a ± 30.2 0.49d ± 0.01 121a ± 18.9 1.12c ± 0.20
SRPP 100 mg/kg 1.90a ± 0.09 16.32b,c ± 2.1 488.1a,b ± 32.8 0.34b ± 0.02 174b ± 22.1 0.94c ± 0.10
SRPP 200 mg/kg 2.10b ± 0.19 13.06b ± 2.6 679.6b ± 9.9 0.22a ± 0.01 208c ± 16.5 0.55a,b ± 0.00
Ranitidine 2.16b ± 0.22 15.22b ± 1.2 505.5a,b ± 35.5 0.39c ± 0.01 136a ± 12.1 0.92b ± 0.10
Serum
Healthy 6.62a ± 0.51 112.3a ± 28 44.20c ± 4.9 0.221a ± 0.004 23.6c ± 3.0 0.165a ± 0.01
Ulcerated 6.84a ± 0.53 264.6d ± 32 22.90a ± 3.1 0.286c ± 0.02 11.1a ± 1.8 0.326d ± 0.02
SRPP 100 mg/kg 6.35a ± 0.59 201.1c ± 36 28.63b ± 2.3 0.298d ± 0.03 16.5b ± 2.1 0.261c ± 0.03
SRPP 200 mg/kg 6.95a ± 0.48 168.2b ± 21 40.12c ± 3.8 0.268b ± 0.03 19.8b,c ±12.9 0.162a ± 0.01
Ranitidine 6.35a ± 0.63 196.3b,c ±23 30.82b ± 2.9 0.226a ± 0.02 12.8a ± 2.6 0.186b ± 0.01
Liver
Healthy 24.2c ± 0.31 261.5b ± 41 28.42d ± 3.1 0.32a ± 0.02 414c ± 51 0.98a ± 0.13
Ulcerated 21.9a ± 0.23 142.4a ± 18 22.18b,c ± 2.6 0.58c ± 0.05 221a ± 26 2.41d ± 0.23
SRPP 100 mg/kg 23.1b ± 0.28 164.2a ± 13 19.63b,c ± 2.4 0.36a,b ± 0.03 315b ± 36 1.84c ± 0.16
SRPP 200 mg/kg 23.9b ± 0.28 361.5d ± 39 15.54a ± 2.1 0.28a ± 0.02 214a ± 24 1.26b ± 0.11
Ranitidine 23.6b ± 0.26 314.4c,d ± 36 17.34a ± 1.9 0.32a ± 0.02 254a ± 28 1.41b ± 0.12

SOD: Superoxide dismutase; GSH: Glutathione; TBARS: Thiobarbituric acid reactive substances. Different letters a to d in the column represents that values are significantly different when compared between ulcer induced with healthy control and SRPP/Ranitidine treated groups.