Table 1. Characteristics of the study population.
Absolute eosinophil counts are significantly different between each eosinophilic group and the normal donor group (P < 0.0001). AEC is also significantly different between the FIP1L1-PDGFRA/JAK2 group and the PARA (P = 0.0279) group as well as between the FIP1L1-PDGFRA/JAK2 group and the HEUS group (P = 0.0076).
| Diagnosis | Median Age (range) |
Sex (M / F) | GMa Eosinophils × 109/L (range) |
|---|---|---|---|
| HES/LHES (n = 13) | 58 (17 – 82) | 9 / 4 | 5.183 (1.514 – 60.920) |
| FIP1L1-PDGFRA/JAK2 (n = 9) | 35 (17 – 78) | 8 / 1 | 5.970 (2.425 – 11.821) |
| PARA (n = 10) | 28.5 (21 – 71) | 5 / 5 | 2.948 (1.071 – 10.400) |
| HEUS (n = 10) | 54.5 (18 – 74) | 7 / 3 | 2.864 (1.340 – 6.390) |
| EAE (n = 2) | 27 (21 – 33) | 2 / 0 | Not Applicable |
| EGID (n = 11) | 34 (22 – 54) | 9 / 2 | 0.173 (0.070 – 0.470) |
| ND (n = 19) | 34 (26 – 81) | 12 / 7 | 0.133 (0.039 – 0.390)b |
a
GM indicates geometric mean
b
Absolute eosinophil counts were available for 14 of the 19 ND.