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. 2014 Aug 7;110:132–141. doi: 10.1016/j.antiviral.2014.07.013

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Copyright © 2014 Elsevier B.V. All rights reserved.

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Fig. 6 — Protective efficacy in B-cell deficient mice treated with VNA and MCP-1after infection with DRV. C57BL/6J and Ighm^tm1Cgn (B-cell deficient) mice (groups of 8) at the age of 4–6 weeks were infected i.m. with 10 IMLD50 DRV-Mexico and then treated with RABV- antibody positive serum (Ab) in conjunction with MCP-1 at 5 dpi or at both 5 and 7 dpi. Infected and treated mice were observed daily for 21 days and survivorship was recorded and analyzed. Asterisks indicate significant differences (^∗p < 0.05, ^∗∗p < 0.01, ^∗∗∗p < 0.001) between the indicated experimental groups.