Table 1.

Demographic and Clinical Characteristics of Patients With FL Enrolled Onto and Randomly Assigned in E4402

Characteristic	All Patients (N = 408)		Randomly Assigned Patients
			RR (n = 143)		MR (n = 146)
	No.	%	No.	%	No.	%
Age, years
Median	59.1		59.7		59.0
Range	25.2-86.4		26.0-86.2		25.2-86.1
< 60	218	53.4	73	51.0	78	53.4
Male sex	195	48	67	47	66	45
White race	387	95	135	94	139	95
PS 0	347	85	120	84	128	88
BM involvement	191	47	62	43	73	50
Elevated β2-microglobulin	171	42	65	46	55	38
Elevated LDH	52	13	18	13	22	15
HgB < 12 g/dL	25	6	12	8	7	5
Stage
I-II	4	1	1	1	2	1
III	201	49	79	55	67	46
IV	202	50	63	44	77	53
FLIPI score
Low	69	17	21	15	23	16
Intermediate	192	47	65	45	66	45
High	147	36	57	40	57	39
FL histology
Grade 1	291	71	101	71	97	66
Grade 2	92	23	33	23	42	29
Grade 3a	8	2	3	2	2	1
Not classifiable	17	4	6	4	5	3
Time since diagnosis < 1 year	376	92	132	92	132	90

Abbreviations: BM, bone marrow; FL, follicular lymphoma; FLIPI, Follicular Lymphoma International Prognostic Index; HgB, hemoglobin; LDH, lactate dehydrogenase; MR, maintenance rituximab; PS, performance status; RR, re-treatment rituximab.