Table 3.
Grade 3 to 5 Toxicities in Randomly Assigned Patients
| Toxicity | Grade |
|||||
|---|---|---|---|---|---|---|
| RR (n = 143) |
MR (n = 146) |
|||||
| 3 | 4 | 5 | 3 | 4 | 5 | |
| Thrombocytopenia | 1 | — | — | — | — | — |
| Neutropenia | — | 2 | — | — | — | — |
| Fever without neutropenia | — | — | — | 1 | — | — |
| Infection without neutropenia | — | — | — | 1 | — | — |
| Fatigue | 1 | — | — | 3 | — | — |
| Hypertension | 1 | — | — | 1 | — | — |
| Insomnia | — | — | — | 1 | — | — |
| Hearing loss | — | — | — | 1 | — | — |
| Generalized weakness | — | — | — | 1 | — | — |
| Encephalopathy | — | — | — | — | — | 1 |
| Syncope | 1 | — | — | — | — | — |
| Larynx pain | — | — | — | 1 | — | — |
| Worst degree | 4 | 2 | — | 10 | — | 1 |
Abbreviations: MR, maintenance rituximab; RR, re-treatment rituximab.