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. 2014 Aug 11;32(28):3126–3136. doi: 10.1200/JCO.2013.54.1086

Table 3.

Sexual Functioning, Symptoms, and Quality of Life for Survivors and Siblings: WHQ and SF-36

Subscale Survivors (n = 2,178)
Siblings (n = 408)
OR* 95% CI P
No. % No. %
WHQ
Depressed mood 1.13 0.90 to 1.43 .3
    > 0-1 1,304 60.2 226 55.5
    0 863 39.8 181 44.5
Somatic symptoms 1.24 0.90 to 1.70 .2
    > 0-1 1,895 87.2 339 83.3
    0 279 12.8 68 16.7
Memory/concentration 1.29 1.03 to 1.63 .03
    > 0-1 1,272 58.6 206 50.5
    0 900 41.4 202 49.5
Vasomotor symptoms 1.27 0.98 to 1.64 .07
    > 0-1 694 31.9 112 27.5
    0 1,480 68.1 296 72.5
Anxiety/fears 1.33 1.06 to 1.68 .01
    > 0-1 1,316 60.7 208 51.1
    0 852 39.3 199 48.9
Sexual behavior 1.17 0.92 to 1.50 .2
    > 0-1 927 49.8 182 49.2
    0 933 50.2 188 50.8
Sleep problems 1.02 0.81 to 1.29 .9
    > 0-1 1,335 61.6 242 59.5
    0 833 38.4 165 40.5
Menstrual problems 0.90 0.69 to 1.17 .4
    > 0-1 1,589 73.1 297 72.8
    0 585 26.9 111 27.2
Attractiveness 1.11 0.89 to 1.40 .4
    > 0-1 1,097 50.5 192 47.1
    0 1,077 49.5 216 52.9
SF-36
Physical functioning 0.39 0.19 to 0.78 .008
    0 to < 40 126 5.8 9 2.2
    ≥ 40 to 100 2,045 94.2 398 97.8
Role—physical 0.68 0.47 to 1.00 .05
    0 to < 40 302 13.9 36 8.9
    ≥ 40 to 100 1,867 86.1 370 91.1
Bodily pain 0.65 0.39 to 1.06 .09
    0 to < 40 173 8.0 21 5.2
    ≥ 40 to 100 1,996 92.0 386 94.8
General health perceptions 0.41 0.27 to 0.61 < .001
    0 to < 40 369 17.0 33 8.1
    ≥ 40 to 100 1,802 83.0 374 91.9
Vitality 0.91 0.72 to 1.14 .4
    0 to < 40 1,073 49.5 183 45
    ≥ 40 to 100 1,095 50.5 224 55
Social functioning 0.64 0.38 to 1.07 .09
    0 to < 40 180 8.3 19 4.7
    ≥ 40 to 100 1,978 91.7 383 95.3
Role—emotional 0.98 0.74 to 1.31 .9
    0 to < 40 497 22.9 81 20
    ≥ 40 to 100 1,669 77.1 323 80
Mental health 1.51 0.91 to 2.51 .1
    0 to < 40 97 4.5 23 5.7
    ≥ 40 to 100 2,072 95.5 384 94.3
Physical summary scale 0.42 0.027 to 0.63 < .001
    0 to < 40 342 15.9 29 7.3
    ≥ 40 to 100 1,809 84.1 371 92.7
Mental summary scale 1.04 0.79 to 1.35 .8
    0 to < 40 559 26.0 96 24.0
    ≥ 40 to 100 1,592 74.0 304 76.0

Abbreviations: OR, odds ratio; SF-36, Medical Outcomes Study Short Form-36; WHQ, Women's Health Questionnaire.

*

Siblings used as referent to compare proportion of score 0 over score 0 to 1 with survivors for WHQ and to compare proportion of t score ≥ 40 to 100 over t score 0 to < 40 with survivors for SF-36.