Table 5.
Psychosexual Functioning Among Survivors With or Without OF: WHQ and SF-36
| Subscale | With OF (n = 235) |
Without OF (n = 1,943) |
OR* | P | ||
|---|---|---|---|---|---|---|
| No. | % | No. | % | |||
| WHQ | ||||||
| Depressed mood | 1.32 | .09 | ||||
| > 0 to 1 | 152 | 64.7 | 1,152 | 59.3 | ||
| 0 | 83 | 35.3 | 780 | 40.1 | ||
| Somatic symptoms | 1.14 | .6 | ||||
| > 0 to 1 | 208 | 88.5 | 1,687 | 86.8 | ||
| 0 | 27 | 11.5 | 252 | 13 | ||
| Memory/concentration | 1.07 | .7 | ||||
| > 0 to 1 | 141 | 60 | 1,131 | 58.2 | ||
| 0 | 93 | 39.6 | 807 | 41.5 | ||
| Vasomotor symptoms | 1.59 | .005 | ||||
| > 0 to 1 | 103 | 43.8 | 591 | 30.4 | ||
| 0 | 132 | 56.2 | 1,348 | 69.4 | ||
| Anxiety/fears | 0.92 | .6 | ||||
| > 0 to 1 | 138 | 58.7 | 1,178 | 60.6 | ||
| 0 | 97 | 41.3 | 755 | 38.9 | ||
| Sexual behavior | 2.36 | < .001 | ||||
| > 0 to 1 | 130 | 55.6 | 797 | 41.7 | ||
| 0 | 65 | 27.8 | 868 | 45.4 | ||
| Sleep problems | 1.53 | .01 | ||||
| > 0 to 1 | 169 | 71.9 | 1,166 | 60 | ||
| 0 | 66 | 28.1 | 767 | 39.5 | ||
| Menstrual problems | 0.58 | .001 | ||||
| > 0 to 1 | 149 | 63.4 | 1,440 | 74.1 | ||
| 0 | 86 | 36.6 | 499 | 25.7 | ||
| Attractiveness | 1.13 | .5 | ||||
| > 0 to 1 | 130 | 55.3 | 967 | 49.8 | ||
| 0 | 105 | 44.7 | 972 | 50 | ||
| SF-36 | ||||||
| Physical functioning | 0.67 | .2 | ||||
| 0 to < 40 | 19 | 8.1 | 107 | 5.5 | ||
| ≥ 40 to 100 | 216 | 91.9 | 1,829 | 94.1 | ||
| Role—physical | 0.61 | .02 | ||||
| 0 to < 40 | 50 | 21.3 | 252 | 13 | ||
| ≥ 40 to 100 | 184 | 78.3 | 1,683 | 86.6 | ||
| Bodily pain | 0.64 | .08 | ||||
| 0 to < 40 | 27 | 11.5 | 146 | 7.5 | ||
| ≥ 40 to 100 | 208 | 88.5 | 1,788 | 92 | ||
| General health perceptions | 0.42 | < .001 | ||||
| 0 to < 40 | 69 | 29.4 | 300 | 15.4 | ||
| ≥ 40 to 100 | 166 | 70.6 | 1,636 | 84.2 | ||
| Vitality | 0.78 | .1 | ||||
| 0 to < 40 | 129 | 54.9 | 944 | 48.6 | ||
| ≥ 40 to 100 | 106 | 45.1 | 989 | 50.9 | ||
| Social functioning | 0.93 | .8 | ||||
| 0 to < 40 | 24 | 10.2 | 156 | 8 | ||
| ≥ 40 to 100 | 209 | 88.9 | 1,769 | 91 | ||
| Role—emotional | 0.89 | .6 | ||||
| 0 to < 40 | 55 | 23.4 | 442 | 22.7 | ||
| ≥ 40 to 100 | 178 | 75.7 | 1,491 | 76.7 | ||
| Mental health | 0.74 | .4 | ||||
| 0 to < 40 | 12 | 5.1 | 85 | 4.4 | ||
| ≥ 40 to 100 | 223 | 94.9 | 1,849 | 95.2 | ||
| Physical summary scale | 0.64 | .03 | ||||
| 0 to < 40 | 56 | 23.8 | 286 | 14.7 | ||
| ≥ 40 to 100 | 175 | 74.5 | 1,634 | 84.1 | ||
| Mental summary scale | 1.09 | .7 | ||||
| 0 to < 40 | 56 | 23.8 | 503 | 25.9 | ||
| ≥ 40 to 100 | 175 | 74.5 | 1,417 | 72.9 | ||
NOTE. Adjusted for age at study, age at primary diagnosis, marital status, education level, income, ethnicity/race, cranial irradiation, and major medical condition.
Abbreviations: OF, ovarian failure; OR, odds ratio; SF-36, Medical Outcomes Study Short Form-36; WHQ, Women's Health Questionnaire.
*
Without OF as referent.