Table 4.
Treatment-Emergent Adverse Events With Severity ≥ Grade 3 (occurring in more than one patient) in Either Sequential or Combination Treatment
| Preferred Term* | Sequential Treatment (n = 13) |
Combination Treatment (n = 26) |
||
|---|---|---|---|---|
| No. | % | No. | % | |
| Any event | 8 | 62 | 19 | 73 |
| Febrile neutropenia | 2 | 15 | 8 | 31 |
| Neutropenia | 2 | 15 | 6 | 23 |
| Anemia | 2 | 15 | 4 | 15 |
| Peripheral sensory neuropathy | 2 | 15 | 2 | 8 |
| Leukopenia | 1 | 8 | 2 | 8 |
| Pulmonary embolism | 0 | 3 | 12 | |
| Septic shock | 1 | 8 | 2 | 8 |
| Syncope | 1 | 8 | 2 | 8 |
| Cardiac failure | 0 | 2 | 8 | |
| Constipation | 2 | 15 | 0 | |
| Fatigue | 2 | 15 | 0 | |
| Respiratory failure | 0 | 2 | 8 | |
*
Medical Dictionary for Regulatory Activities, Version 14.0.