Table A1.
Treatment-Emergent Adverse Events (incidence ≥ 10%) in Combination Treatment
| Preferred Term* | Combination Treatment (n = 26) |
|
|---|---|---|
| No. | % | |
| Any event | 26 | 100 |
| Peripheral sensory neuropathy | 18 | 69 |
| Nausea | 17 | 65 |
| Diarrhea | 15 | 58 |
| Fatigue | 15 | 58 |
| Alopecia | 14 | 54 |
| Dyspnea | 12 | 46 |
| Constipation | 10 | 38 |
| Peripheral edema | 9 | 35 |
| Anemia | 8 | 31 |
| Chills | 8 | 31 |
| Febrile neutropenia | 8 | 31 |
| Myalgia | 8 | 31 |
| Upper respiratory tract infection | 8 | 31 |
| Anxiety | 7 | 27 |
| Back pain | 7 | 27 |
| Cough | 7 | 27 |
| Headache | 7 | 27 |
| Hypokalemia | 7 | 27 |
| Insomnia | 7 | 27 |
| Pyrexia | 7 | 27 |
| Decreased appetite | 6 | 23 |
| Hypomagnesemia | 6 | 23 |
| Neutropenia | 6 | 23 |
| Pain in extremity | 6 | 23 |
| Abdominal pain | 5 | 19 |
| Arthralgia | 5 | 19 |
| Dizziness | 5 | 19 |
| Dry skin | 5 | 19 |
| Rash | 5 | 19 |
| Vomiting | 5 | 19 |
| Weight decreased | 5 | 19 |
| Depression | 4 | 15 |
| Hot flush | 4 | 15 |
| Nasal congestion | 4 | 15 |
| Rash, maculopapular | 4 | 15 |
| Rash, pruritic | 4 | 15 |
| Urinary tract infection | 4 | 15 |
| Chest pain | 3 | 12 |
| Deep vein thrombosis | 3 | 12 |
| Dehydration | 3 | 12 |
| Dysuria | 3 | 12 |
| Hyperhidrosis | 3 | 12 |
| Muscular weakness | 3 | 12 |
| Musculoskeletal pain | 3 | 12 |
| Peripheral motor neuropathy | 3 | 12 |
| Pruritis | 3 | 12 |
| Pulmonary embolism | 3 | 12 |
| Vision blurred | 3 | 12 |
*
Medical Dictionary for Regulatory Activities, version 14.0.