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. Author manuscript; available in PMC: 2014 Sep 23.
Published in final edited form as: Cochrane Database Syst Rev. 2008 Oct 8;(4):CD005124. doi: 10.1002/14651858.CD005124.pub2
Methods Randomisation performed by biostatistician using computer generated random numbers. Providers in the intervention group attended a training session on the use of the ALPHA questionnaire. Control group provided usual care. Women were seen once in pregnancy and reviewed at 1 month postpartum.
As per the primary study described in Carroll 2005, in addition the EDS was also administered at 6 weeks postpartum to identify women with postpartum depression
Participants 21 providers (midwives, obstetricians, and family physicians) assigned to the ALPHA condition and 27 assigned to the control condition. Providers saw 227 pregnant women (98 ALPHA group, 129 control) between 12-30 weeks’ gestation.
98 women receiving the ALPHA psychosocial questionnaire; 129 controls
Interventions The ALPHA, a psychosocial health assessment questionnaire, given antenatally; the control group received usual antenatal care
Outcomes The study compared the capacity of ALPHA group providers vs. control providers in identifying psychosocial risk factors. A secondary aim was to examine the relationship between the presence and number of antenatal risk factors and a postnatal EPDS score > 9
Notes Bias may have occurred with greater ALPHA than control provider dropout. 72.7% women comfortable with discussing psychosocial issues; 64% of those providers responding found the ALPHA easy to use and 86% would use it routinely if it was recommended.
This review undertook re-analysis of the data and reported an OR of 1.64 (vs. OR 1.8 reported by authors in published article).
Blackmore 2006 performed a secondary analysis of the Carroll 2005 data focusing on postpartum outcome as a function of the administration of the ALPHA antenatally
Risk of bias
Item Authors’ judgement Description
Allocation concealment? Yes A - Adequate