Table 2.
Genotype and allele frequencies of the VEGF -460C/T and +405G/C polymorphisms in PCOS patients and controls
| Genotypes/Alleles | PCOS (%) n = 126 | Controls (%) n = 130 | ‘P’-value | Odds ratio | 95 % CI |
|---|---|---|---|---|---|
| + 405 G/C Genotypes | |||||
| G/G | 70 (55.5) | 52 (40.0) | 0.03023a | ||
| G/C | 46 (36.5) | 59 (45.3) | |||
| C/C | 10 (7.9) | 19 (14.6) | |||
| Alleles | |||||
| G | 186 (0.74) | 163 (0.63) | 0.00694b | 1.6771 | 1.1505-2.4447 |
| C | 66 (0. 26) | 97 (0.37) | |||
| - 460 C/T Genotypes | |||||
| T/T | 40 (31.7) | 33 (25.3) | 0.37232a | ||
| T/C | 59 (46.8) | 72 (55.3) | |||
| C/C | 27 (21.4) | 25 (19.2) | |||
| Alleles | |||||
| T | 139 (0.55) | 138 (0.53) | 0.63676b | 1.0875 | 0.768 –1.5398 |
| C | 113 (0.45) | 122 (0. 47) | |||
CI, confidence interval
a Fisher’s exact test (3 × 2 table at 2 df); P < 0.05
b Fisher’s exact test (2 × 2 table at 1 df); P < 0.05