Kajikawa 1994.

Methods	Design: Randomised controlled trial. Setting: Japan.
Participants	N = 42 patients (32 male, 10 female) undergoing hepatectomy for hepatocellular carcinoma. NB: No demographic data provided. Exclusion criteria: Hematocrit level < 33.0%.
Interventions	PAD group (n = 21) Control group (n = 21) Timing of autologous blood collection/retransfusion: Donation beginning 2 to 3 weeks before the operation. Volume of autologous blood collected/retransfused: 400 mL (2 units) autologous blood was collected once or twice weekly (total = 400 to 1200 mL) from each patient. Iron supplementation: PAD patients received 80 mg iron sulphate and 500 mL of Ringer's lactate solution intravenously on the day of blood collection, followed by 100 mg iron sulphate given orally once daily until the operation. Use of transfusion threshold: Not reported. Length of surgery: Mean ± sem = 318 ± 23 and 290 ± 20 minutes in the PAD and control groups respectively.
Outcomes	Outcomes reported: number of patients exposed to allogeneic blood (n), allogeneic blood transfusion (units), blood loss (mL), mortality (n), complications (n).
Notes	Period of study: August 1991 and November 1992. Length of study: Not reported. A priori sample size: Not reported. Baseline comparability: Not reported.
Risk of bias
Bias	Authors' judgement	Support for judgement
Adequate sequence generation?	Unclear risk	No information.
Allocation concealment?	Unclear risk	No information.
Blinding? All outcomes	High risk	Not blinded.
Intention‐to‐treat analysis?	Low risk	Data were analysed on an intention‐to‐treat basis.