Kostopanagiotou 2007.
Methods | Design: Randomised controlled trial. Setting: Greece | |
Participants | N = 35, liver resection patients.
Inclusion criteria: Pre‐operative haematocrit within normal levels. Exclusion criteria: Patients with co‐morbid diseases, cirrhosis or receiving immunosuppressive medication were excluded. |
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Interventions |
Timing of autologous blood collection/retransfusion: no details presented. Volume of autologous blood collected/retransfused: 2 units. Patients in PAD group who needed more than the 2 units and those (in either group) who did not require transfusion were excluded from the analysis. Iron supplementation: Not mentioned. Use of transfusion threshold: Serum haemoglobin levels were maintained at > 9.0 g/dL. Length of surgery: Mean ± SD = 175 ± 45 and 190 ± 50 minutes in the PAD and control groups respectively. |
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Outcomes |
Outcomes reported: Number exposed to autologous and allogeneic blood*, length of hospital stay, mortality. [*These outcome data were not presented in the trial report, obtained from author.] |
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Notes | Period of study: Not reported. Length of study: Patients followed up for 1 year after surgery. A priori sample size: Not reported. Baseline comparability: Reported that demographics and type of surgery were similar in both groups. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Adequate sequence generation? | Unclear risk | No information. |
Allocation concealment? | Unclear risk | No information. |
Blinding? All outcomes | Unclear risk | No information. |
Intention‐to‐treat analysis? | Low risk | Data were analysed on an intention‐to‐treat basis. |