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. 2001 Oct 23;2001(4):CD003602. doi: 10.1002/14651858.CD003602

Kostopanagiotou 2007.

Methods Design: Randomised controlled trial. 
 Setting: Greece
Participants N = 35, liver resection patients.
  • PAD group = M/F = 9/6, age (mean ± SD) = 52 ± 11.

  • Control group = M/F = 8/5, age (mean ± SD) = 51 ± 10


Inclusion criteria: Pre‐operative haematocrit within normal levels. 
 Exclusion criteria: Patients with co‐morbid diseases, cirrhosis or receiving immunosuppressive medication were excluded.
Interventions
  • PAD group (n = 19)

  • Control group (n = 16)


Timing of autologous blood collection/retransfusion: no details presented. 
 Volume of autologous blood collected/retransfused: 2 units. Patients in PAD group who needed more than the 2 units and those (in either group) who did not require transfusion were excluded from the analysis. 
 Iron supplementation: Not mentioned. 
 Use of transfusion threshold: Serum haemoglobin levels were maintained at > 9.0 g/dL. 
 Length of surgery: Mean ± SD = 175 ± 45 and 190 ± 50 minutes in the PAD and control groups respectively.
Outcomes Outcomes reported: Number exposed to autologous and allogeneic blood*, length of hospital stay, mortality.
[*These outcome data were not presented in the trial report, obtained from author.]
Notes Period of study: Not reported. 
 Length of study: Patients followed up for 1 year after surgery. 
 A priori sample size: Not reported. 
 Baseline comparability: Reported that demographics and type of surgery were similar in both groups.
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation? Unclear risk No information.
Allocation concealment? Unclear risk No information.
Blinding? 
 All outcomes Unclear risk No information.
Intention‐to‐treat analysis? Low risk Data were analysed on an intention‐to‐treat basis.