Summary of findings for the main comparison. INDIVIDUAL PSYCHODYNAMIC PSYCHOTHERAPY versus MEDICATION for schizophrenia and severe mental illness.
| INDIVIDUAL PSYCHODYNAMIC PSYCHOTHERAPY versus MEDICATION for schizophrenia and severe mental illness | ||||||
| Patient or population: patients with schizophrenia and severe mental illness Settings: in hospital Intervention: INDIVIDUAL PSYCHODYNAMIC PSYCHOTHERAPY versus MEDICATION | ||||||
| Outcomes | Illustrative comparative risks* (95% CI) | Relative effect (95% CI) | No of Participants (studies) | Quality of the evidence (GRADE) | Comments | |
| Assumed risk | Corresponding risk | |||||
| Control | INDIVIDUAL PSYCHODYNAMIC PSYCHOTHERAPY versus MEDICATION | |||||
| Committed suicide by three years | 42 per 1000 | 22 per 1000 (2 to 234) | RR 0.52 (0.05 to 5.56) | 94 (1 study) | ⊕⊕⊝⊝ low1,2 | |
| Global impression: 1. Not able to be discharged (long term) | 42 per 1000 | 351 per 1000 (85 to 1000) | RR 8.35 (2.03 to 34.3) | 94 (1 study) | ⊕⊕⊝⊝ low1,2 | |
| Global impression: 2. Given medication during 12 months to three years follow up ‐ by 12 months | 958 per 1000 | 613 per 1000 (479 to 776) | RR 0.64 (0.5 to 0.81) | 94 (1 study) | ⊕⊕⊝⊝ low1,2 | |
| Global impression: 2. Given medication during 12 months to three years follow up ‐ by three years | 1000 per 1000 | 850 per 1000 (750 to 960) | RR 0.85 (0.75 to 0.96) | 94 (1 study) | ⊕⊕⊝⊝ low1,2 | |
| *The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). CI: Confidence interval; RR: Risk ratio; | ||||||
| GRADE Working Group grades of evidence High quality: Further research is very unlikely to change our confidence in the estimate of effect. Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate. Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate. Very low quality: We are very uncertain about the estimate. | ||||||
1 Randomisation undertaken but not clearly described. 2 One small single study.