1. . Suggested design of study.
Methods | Allocation: randomised, block, fully explicit description. Blinding: single, tested. Duration: 12 weeks treatment, and then follow up to at least 26 weeks. |
Participants | Diagnosis: schizophrenia (ICD). N=300.* Age: adults. Sex: both. |
Interventions | 1. Individual Psychodynamic Psychotherapy. N=150. 2. Standard care. N=150. |
Outcomes | General: time to all‐cause treatment failure marked by its discontinuation, relapse, general impression of clinician (CGI), career/other (CGI), compliance with treatment., healthy days, Mental state: CGI. Quality of life. CGI. Family burden: CGI. Social functioning: return to everyday living for 80% of time.* Adverse events: any adverse event recorded. Economic outcomes. |
Notes | * Powered to be able to identify a difference of ˜20% between groups for primary outcome with adequate degree of certainty. |