Figure 1. Galectin-3 deficient mice showed delayed colonisation and clearance, and normal crypt hyperplasia after C.rodentium infection.

A. Scheme of the protocol used for infection and sampling; B. The colony forming units (cfu) of C. rodentium shed per gram of stool by infected C57BL/6 wild-type controls (open circles) and infected Galectin-3 knockout (Lgals3 ^−/−) mice (closed circles) is shown per day after infection. Values indicate the median and interquartile range of groups of 11 animals; C. Crypt length at day 15 post infection. Dots indicate the average crypt length per mouse, while horizontal lines indicate the average per group of mice (n = 2–4 for uninfected mice and 9–11 for infected mice). Data was obtained from 2 independent infection experiments, an asterisk indicates a statistically significant difference (p<0.02) and “ns” means no significant difference (p>0.05) between Lgals3 ^−/− and C57BL/6 wild-type controls.