Figure 2. Galectin-3 deficient mice showed reduced inflammatory infiltrates into lamina propria and enhanced expression of IL-6 and KC.

A. Number of CD3⁺ cells, CD4⁺ cells, CD8⁺ cells, macrophages (M_Φ), dendritic cells (DC) and endogenous peroxidase-containing (EPC) cells or neutrophils per 250 µm² of colonic lamina propria in C. rodentium infected mice. Bars indicate the average for each group of 10 C57BL/6 wild-type and Lgals3 ^−/− animals; B. Data show cytokine and chemokines levels as pg per mg of total proteins in the colonic tissue of Lgals3 ^−/− and C57BL/6 wild-type control mice. Data fit Gaussian distribution, bars represent the mean cytokine expression for groups of 10 mice while error bars indicate the SEM. Data was obtained from 2 independent infection experiments. An asterisk indicates a statistically significant difference (p≤0.05) and “ns” means no significant difference (p>0.05) between groups of galectin deficient and control mice.