Figure 4. Galectin-1 deficient mice showed increased neutrophil and DC infiltrates and enhanced expression of IL-6 and KC.

A. Number of CD3⁺ cells, CD4⁺ cells, CD8⁺ cells, macrophages (M_Φ), endogenous peroxidase-containing (EPC) cells (most commonly neutrophils) and DC (dendritic cells) per 250 µm² of colonic lamina propria in C. rodentium infected mice. Bars indicate the average for each group of 10 C57BL/6 wild-type and Lgals1^−/− animals; B. Data show cytokines and chemokine levels as pg per mg of total proteins in the colonic tissue of Lgals1^−/− and C57BL/6 wild-type control mice. Data fit Gaussian distribution, bars represent the mean expression for groups of 10 mice while error bars indicate the SEM. Data was obtained from 2 independent infection experiments, an asterisk indicates a statistically significant difference (p≤0.05) and “ns” means no significant difference (p>0.05) between galectin and wild-type control mice.