Table 2. SNP genotyped, their location within the gene, position within galGal version 4, nucleotide change, and codon affected, and the MX protein domain involved.
SNP | Location | GGA1 bp | nt change1 | Codon | AA | Domain3 | Ref |
MxP-2242 | Promoter | 108,275,357 | G>C | - | - | - | [24], [36] |
MxP-158 | Promoter | 108,275,433 | A>T | - | - | - | [36] |
MxP-142 | Promoter | 108,275,449 | C>G | - | - | - | [36] |
MxP-136 | Promoter | 108,275,455 | C>T | - | - | - | [36] |
MxP-55 | Promoter | 108,275,536 | G>A | - | - | - | [36] |
MxP-18 | Promoter | 108,275,573 | T>C | - | - | - | [36] |
Mx5U322 | Exon 1 | 108,275,623 | A>C | - | - | - | [24], [36] |
Mx5U422 | Exon 1 | 108,275,633 | T>C | - | - | - | [24], [36] |
Mx5U100 | Exon 2 | 108,280,332 | A>C | - | - | - | [24] |
Mx5U104 | Exon 2 | 108,280,336 | A>G | - | - | - | [24], [36] |
Mx5U117 | Exon 2 | 108,280,349 | A>T | - | - | - | |
Mx5U118 | Exon 2 | 108,280,350 | G>A | - | - | - | [24] |
MxCDS13 | Exon 2 | 108,280,385 | C>T | CGG>TGG | R5W | ND | [5], [13] |
MxCDS62 | Exon 2 | 108,280,434 | G>A | CGG>CAG | R21Q | ND | [5], [8], [10], [13] |
MxCDS122 | Exon 2 | 108,280,494 | C>G | CCA>CGA | P41R | ND | [5], [8], [10], [13] |
MxCDS125 | Exon 2 | 108,280,497 | T>C | TTA>TCA | L42S | ND | [5], [8], [10], [13] |
MxCDS156 | Exon 2 | 108,280,528 | T>A | GCT>GCA | A52A | ND | [5], [8], [10] |
MxCDS254* | Exon 3 | 108,282,234 | T>C | TTG>TCG | L85S | ND | [5] |
MxCDS281 | Exon 3 | 108,282,261 | G>A | CGA>CAA | R94Q | BSE1 | [5], [10] |
MxCDS351 | Exon 3 | 108,282,331 | T>C | ATT>ATC | I117I | G-domain | [5], [8] |
MxCDS554* | Exon 4 | 108,283,451 | A>G | AAA>AGA | K185R | G-domain | [5], [13] |
MxCDS595* | Exon 5 | 108,285,185 | G>A | GGT>AGT | G199S | G-domain | [5], [13] |
MxCDS605 | Exon 5 | 108,285,194 | G>C | AGT>ACT | S202T | G-domain | [5], [8], [13] |
MxCDS694 | Exon 5 | 108,285,283 | G>A | GGG>AGG | G232R | G-domain | [5] |
MxCDS696 | Exon 5 | 108,285,285 | G>C | GGG>GGC | G232G | G-domain | [5], [8], [13] |
MxCDS792 | Exon 6 | 108,286,581 | T>C | AAT>AAC | N264N | G-domain | [5], [10] |
MxCDS813 | Exon 6 | 108,286,602 | A>G | GAA>GAG | E271E | G-domain | [5], [10], [13] |
MxCDS922 | Exon 7 | 108,287,175 | G>A | GTA>ATA | V308I | G-domain | [5], [8], [10], [13] |
MxCDS1015 | Exon 7 | 108,287,268 | A>G | ACA>GCA | T339A | G-domain | [5], [8], [10], [13] |
MxCDS1203* | Exon 9 | 108,289,299 | A>C>G | CTA>CTC>CTG | L401L | BSE2 | [3], [5], [8] |
MxCDS1248 | Exon 9 | 108,289,344 | A>G | ACA>ACG | T416T | MD | [5], [8] |
MxCDS1329 | Exon 10 | 108,289,898 | C>T | AAC>AAT | N443N | MD | [5] |
MxCDS1455 | Exon 11 | 108,290,956 | C>T | CGC>CGT | R485R | MD | [5], [8] |
MxCDS1545 | Exon 11 | 108,291,046 | G>A | GCG>GCA | A515A | MD | [5], [8], [10] |
MxCDS1643 | Exon 13 | 108,293,825 | C>T | GCC>GTC | A548V | MD | [5], [8], [13] |
MxCDS1747 | Exon 13 | 108,293,929 | A>G | ACA>GCA | T583A | MD/GED | [5], [10], [13] |
MxCDS1801 | Exon 13 | 108,293,983 | A>C | AAA>CAA | K601Q | MD/GED | |
MxCDS1892 | Exon 14 | 108,295,901 | G>A | AGT>AAT | S631N | GED | [5], [8], [13] |
MxCDS1905 | Exon 14 | 108,295,914 | C>A | AGC>AGA | S635R | GED | |
MxCDS2019 | Exon 14 | 108,296,028 | G>A | CAG>CAA | Q673Q | Hinge1 | [5], [8] |
galGal4 > variant.
Denotes SNP that were reported in the literature, but were not genotyped in the elite lines. Examination of the resequence data indicates that all haplotypes had the variant allele at these SNP.
Mx protein domain; ND = domain not determined, BSE = bundle signaling element, G-domain = GTPase domain, MD = Middle domain, GED = GTPase effector domain, MD/GED = transition region between MD and GED, Hinge = protine hinge region.
*Denotes SNP previously reported in the literature and found not segregating in the elite lines.