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. 2014 Sep 22;9(9):e108054. doi: 10.1371/journal.pone.0108054

Table 2. SNP genotyped, their location within the gene, position within galGal version 4, nucleotide change, and codon affected, and the MX protein domain involved.

SNP Location GGA1 bp nt change1 Codon AA Domain3 Ref
MxP-2242 Promoter 108,275,357 G>C - - - [24], [36]
MxP-158 Promoter 108,275,433 A>T - - - [36]
MxP-142 Promoter 108,275,449 C>G - - - [36]
MxP-136 Promoter 108,275,455 C>T - - - [36]
MxP-55 Promoter 108,275,536 G>A - - - [36]
MxP-18 Promoter 108,275,573 T>C - - - [36]
Mx5U322 Exon 1 108,275,623 A>C - - - [24], [36]
Mx5U422 Exon 1 108,275,633 T>C - - - [24], [36]
Mx5U100 Exon 2 108,280,332 A>C - - - [24]
Mx5U104 Exon 2 108,280,336 A>G - - - [24], [36]
Mx5U117 Exon 2 108,280,349 A>T - - -
Mx5U118 Exon 2 108,280,350 G>A - - - [24]
MxCDS13 Exon 2 108,280,385 C>T CGG>TGG R5W ND [5], [13]
MxCDS62 Exon 2 108,280,434 G>A CGG>CAG R21Q ND [5], [8], [10], [13]
MxCDS122 Exon 2 108,280,494 C>G CCA>CGA P41R ND [5], [8], [10], [13]
MxCDS125 Exon 2 108,280,497 T>C TTA>TCA L42S ND [5], [8], [10], [13]
MxCDS156 Exon 2 108,280,528 T>A GCT>GCA A52A ND [5], [8], [10]
MxCDS254* Exon 3 108,282,234 T>C TTG>TCG L85S ND [5]
MxCDS281 Exon 3 108,282,261 G>A CGA>CAA R94Q BSE1 [5], [10]
MxCDS351 Exon 3 108,282,331 T>C ATT>ATC I117I G-domain [5], [8]
MxCDS554* Exon 4 108,283,451 A>G AAA>AGA K185R G-domain [5], [13]
MxCDS595* Exon 5 108,285,185 G>A GGT>AGT G199S G-domain [5], [13]
MxCDS605 Exon 5 108,285,194 G>C AGT>ACT S202T G-domain [5], [8], [13]
MxCDS694 Exon 5 108,285,283 G>A GGG>AGG G232R G-domain [5]
MxCDS696 Exon 5 108,285,285 G>C GGG>GGC G232G G-domain [5], [8], [13]
MxCDS792 Exon 6 108,286,581 T>C AAT>AAC N264N G-domain [5], [10]
MxCDS813 Exon 6 108,286,602 A>G GAA>GAG E271E G-domain [5], [10], [13]
MxCDS922 Exon 7 108,287,175 G>A GTA>ATA V308I G-domain [5], [8], [10], [13]
MxCDS1015 Exon 7 108,287,268 A>G ACA>GCA T339A G-domain [5], [8], [10], [13]
MxCDS1203* Exon 9 108,289,299 A>C>G CTA>CTC>CTG L401L BSE2 [3], [5], [8]
MxCDS1248 Exon 9 108,289,344 A>G ACA>ACG T416T MD [5], [8]
MxCDS1329 Exon 10 108,289,898 C>T AAC>AAT N443N MD [5]
MxCDS1455 Exon 11 108,290,956 C>T CGC>CGT R485R MD [5], [8]
MxCDS1545 Exon 11 108,291,046 G>A GCG>GCA A515A MD [5], [8], [10]
MxCDS1643 Exon 13 108,293,825 C>T GCC>GTC A548V MD [5], [8], [13]
MxCDS1747 Exon 13 108,293,929 A>G ACA>GCA T583A MD/GED [5], [10], [13]
MxCDS1801 Exon 13 108,293,983 A>C AAA>CAA K601Q MD/GED
MxCDS1892 Exon 14 108,295,901 G>A AGT>AAT S631N GED [5], [8], [13]
MxCDS1905 Exon 14 108,295,914 C>A AGC>AGA S635R GED
MxCDS2019 Exon 14 108,296,028 G>A CAG>CAA Q673Q Hinge1 [5], [8]
1

galGal4 > variant.

2

Denotes SNP that were reported in the literature, but were not genotyped in the elite lines. Examination of the resequence data indicates that all haplotypes had the variant allele at these SNP.

3

Mx protein domain; ND  =  domain not determined, BSE  =  bundle signaling element, G-domain  =  GTPase domain, MD  =  Middle domain, GED  =  GTPase effector domain, MD/GED  =  transition region between MD and GED, Hinge  =  protine hinge region.

*Denotes SNP previously reported in the literature and found not segregating in the elite lines.