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. 2014 Sep 13;14:667. doi: 10.1186/1471-2407-14-667

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© Chapman et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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The receiver operating characteristic (ROC) curve for various ratiometric threshold criteria values for probe positivity from the entire group of 401 gamma detection probe measurement sets is illustrated. The ROC curve ranges from target-to-background ratios of −1-to-1 to 9-to-1 above the mean background count rate. The 1.5-to-1 ratiometric operating point is indicated by (*). The 1.33-to-1 (optimal) ratiometric operating point is indicated by (+). The area under the ROC curve is 0.7150 (71.5%).