Figure 4.

Abundance distributions of the 33 functional genes in response to cirrhosis. This is a heat map showing abundance distributions of the 33 functional genes in response to cirrhosis. The colume is sample, with the sample name and cluster matrix on the top of the figure. The row is the gene signal intensity, with the gene name on the right. The color intensity indicates difference in signal intensities. To show the distribution of the genes with lower abundance, the colored squares of each row were scaled to indicate the relative ratios of the genes among 42 subjects. “*” behind the gene name indicated this gene was found significantly (p < 0.05) lower in HBC than in CT, and even lower in ALC than in HBC samples. “∆” indicated the gene was correlated significantly with Child-Pugh score. The number in front of the gene names indicated the functional category which they belong to. 1. Amino acid biosynthesis and metabolism; 2. Carbohydrate metabolism; 3. Glycan biosynthesis and metabolism; 4. Nucleotide metabolism; 5. Cofactor biosynthesis; 6. Lipid metabolism; 7. Isoprenoid biosynthesis.