Table 1.
Patients clinical and gastroenterological findings
| Patient (gender) | GI*symptoms | Age at diagnosis (years) | Upper GI tract findings ( pathological findings) | Lower GI tract findings ( pathological findings) | Treatment | Other clinical manifestations |
|---|---|---|---|---|---|---|
| II 1 (F) | Heartburn | 71 | Peptic esophagitis Esophagus Papilloma Non haemorrhagic gastritis Duodenum diverticulitis (Duodenal and antrum amyloidosis plus antrum atrophy) | Colon tubular polyp (amyloidosis) | PPI# | Sicca syndrome |
| III 2 (M) | Heartburn | 41 | (Gastric amyloidosis) | - | - | - |
| III 6 (F) | Heartburn Nausea Dyspepsia GOR** | 51 | Erythematous gastritis, Bulbar ulcer. (Gastric amyloidosis) | Normal | PPI# | Sicca syndrome Hepatomegaly Mesenteric lymphadenopathy |
| III 9 (F) | Rectal hemorrhage Diarrhea | 46 | Erythematous gastritis, Antrum ulcer (Gastric and duodenal amyloidosis) | Hemorrhagic rectocolitis Colon polyp (recto colic amyloidosis ) | PPI#MSZ§ | - |
| IV 2 (F) | Heartburn | 28 | - | - | - | - |
| IV 3 (F) | Heartburn | 33 | - | - | - | - |
| IV 4 (F) | Heartburn | 34 | Gastric ulcer | - | - | GallbladerAmyloidos |
| IV 5 (M) | Heartburn | 24 | Erythematous and atrophic gastritis (Gastric amyloidosis) | (recto colic amyloidosis) | - | - |
| IV 7 (F) | Abdominal pain Rectal hemorrhage | 27 | (Gastric amyloidosis) | IBD aspect (recto colic amyloidosis ) | MSZ§ | - |
*Gastro intestinal (GI) ; **Gastroesophageal reflux (GOR); #proton pump inhibitors (PPI); §Mesalazine (MSZ).