Table 1. Cytotoxicity of 4EGI-1 isomers on breast CSCs and breast cancer cells.
BCSCs and breast cancer cells | IC50 of [E]-4EGI-1(μM) | IC50 of [Z]-4EGI-1(μM) |
---|---|---|
SKBR-3 | 30±1.5 | 29±1.3 |
MCF-7 | 30±0.9 | 30±1.1 |
MDA-MB-231 | 32±1.2 | 30±1.4 |
Non-BCSCs of HMLER(CD44high/CD24low)SA | 24±1.1 | 22±0.7 |
BCSCs of HMLER(CD44high/CD24low)FA | 11±0.8 | 10±0.6 |
Note: IC50 means inhibitory concentration that leads to 50% cell viability decrease.