Table 2. Univariate and multivariate analyses of overall survival of gastric cancer patients.
| Variables | n | Univariate analyses | mulvariate analyses | ||||
|---|---|---|---|---|---|---|---|
| HR | (95% CI) | P value | HR | (95% CI) | P value | ||
| age(year) | 0.285 | ||||||
| <60 | 31 | 1.000 | |||||
| ≥60 | 59 | 1.367 | 0.771-2.422 | ||||
| gender | 0.356 | ||||||
| male | 62 | 1.000 | |||||
| female | 28 | 1.296 | 0.747-2.246 | ||||
| tumor size(cm) | 0.016* | 0.139 | |||||
| ≤5 | 41 | 1.000 | 1.000 | ||||
| >5 | 49 | 1.972 | 1.135-3.424 | 1.538 | 0.869-2.720 | ||
| Tumor infiltration | 0.044* | 0.810 | |||||
| T1/T2 | 11 | 1.000 | 1.000 | ||||
| T3 | 56 | 2.985 | 0.917-9.718 | 1.546 | 0.414-5.766 | ||
| T4 | 23 | 4.52 | 1.322-15.446 | 1.541 | 0.368-6.455 | ||
| Local lymph node metastasis | <0.001* | 0.003* | |||||
| N0 | 25 | 1.000 | 1.000 | ||||
| N1 | 10 | 3.851 | 1.171-12.663 | 5.166 | 1.506-17.726 | ||
| N2 | 26 | 5.734 | 2.142-15.351 | 4.138 | 1.437-11.915 | ||
| N3 | 29 | 7.957 | 3.012-21.023 | 6.509 | 2.389-17.739 | ||
| Distant metastasis | 0.100 | ||||||
| M0 | 89 | 1.000 | |||||
| M1 | 1 | 5.467 | 0.722-41.396 | ||||
| Grade | 0.192 | ||||||
| I/II | 6 | 1.000 | |||||
| III | 63 | 1.967 | 0.885-4.383 | ||||
| IV | 11 | 1.293 | 0.435-3.849 | ||||
| FBXO31 | 0.004* | 0.026* | |||||
| Negative | 47 | 1.000 | 1.000 | ||||
| Positive | 43 | 0.440 | 0.254-0.764 | 0.500 | 0.271-0.919 | ||
HR, hazard ratio;
CI, confidence interval;
n Numbers of cases in each group;
*
Statistically significant(P<0.05).