Table 4. Multivariate survival analysis for MSI after treatment with radiotherapy.
| Disease-free survival | Cancer-specific survival | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Whole series | Diploid tumors | Whole series | Diploid tumors | |||||||||
| (No. of patients = 85) | (No. of patients = 73) | (No. of patients = 89) | (No. of patients = 74) | |||||||||
| (No. of events = 25) | (No. of events = 19) | (No. of events = 25) | (No. of events = 17) | |||||||||
| Characteristic | HR (95%CI) | Wald Χ2 | p-value | HR (95%CI) | Wald Χ2 | p-value | HR (95%CI) | Wald Χ2 | p-value | HR (95%CI) | Wald Χ2 | p-value |
| Age (years) | 1.0 (1.0-1.1) | 3.0 | 0.08 | 1.1 (1.0-1.1) | 3.7 | 0.06 | 1.1 (1.0-1.1) | 6.0 | 0.01 | 1.1 (1.0-1.1) | 4.6 | 0.03 |
| Stage | 0.03 | 0.30 | 0.00 | 0.07 | ||||||||
| I | 1* | 1* | 1* | |||||||||
| II | 0.17 | 2.6 (0.9-7.8) | 3.0 | 0.08 | 4.1 (1.1-14.9) | 4.7 | 0.03 | |||||
| III | 4.5 (1.5-13.3) | 7.1 | 0.01 | 7.5 (2.5-22.9) | 12.5 | 0.00 | 4.1 (0.9-20.0) | 3.2 | 0.07 | |||
| Grade | 0.16 | - | 0.06 | - | ||||||||
| '1 | 1* | |||||||||||
| '2 | 0.21 | |||||||||||
| '3 | 3.9 (1.3-11.7) | 5.7 | 0.02 | |||||||||
| MS status | ||||||||||||
| MSS | 1* | 1* | ||||||||||
| MSI | 0,23 | 3.6 (1.2-10.7) | 5.4 | 0.02 | 0.73 | 3.4 (1.1-11.1) | 4.2 | 0.04 | ||||
*
Reference category
HR (95%CI) = hazard ratio (95% confidence interval)