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. 2014 Jul 23;5(15):6466–6483. doi: 10.18632/oncotarget.2238

Table 3. Synopsis of patient data.

Patient characteristics (top), target and effector cell content (center) and specific antibody binding capacity for CD3, CD19, CD20 and CD33 of malignant cells in the peripheral blood as determined with the QIFIKIT (Dako) (bottom).

Patient 1 (green) Patient 2 (red) Patient 3 (blue) Patient 4 (yellow) Patient 5 (purple)
Gender Male Male Male Female Male
Age 19 years 86 years 78 years 67 years 52 years
Diagnosis Mixed phenotype acute leukemia (MPAL (NOS)) CD19-positive NHL with leukemic progression B-CLL Relapsed B-CLL B-CLL
Blast titer 93.4% blasts in BM at diagnosis 58% of lymphocytes in the PB are CD19-positive 29,000 B-CLL cells/μL 65% lymphocytes in the PB (9% atypical) 42% lymphocytes in the PB
Case history newly diagnosed newly diagnosed newly diagnosed 4 years prior: 6x MabThera® plus fludarabine and cyclophosphamide > CR newly diagnosed
% CD19+ in PBMCs 94.8 21 89.8 68.8 73.2
% CD3+ in PBMCs 0.8 56.1 6.8 16.6 8.6
Specific antibody binding capacity (SABC) of tumour cells in the peripheral blood CD3 211 n.d. n.d. n.d. n.d.
CD19 8,400 ± 2,800 14,600 ± 7,700 9,600 ± 500 6,500 ± 1,700 7,600 ± 1,900
CD20 0 19,400 ± 2,200 4,000 ± 100 1,800 ± 300 3,900 ± 1,200
CD33 317 n.d. n.d. n.d. n.d.