Table 4. Synopsis of maximum lysis and EC50 values for patient samples.
Maximum Specific Lysis [%] | EC50 [pM] (95% CI [pM]) | ||||||
---|---|---|---|---|---|---|---|
19-3 | 19-3-19 | MabThera® | 19-3 | 19-3-19 | MabThera® | ||
Patient 1 | 79.3 | 70.8 | n.d. | 1.2 (0.3 - 5) | 48.1 (9 - 270) | n.d. | |
Patient 2 | 61.5 | 59.2 | 72.8 | 6.1 (4 - 10) | 4.8 (3 - 9) | 185.7 (135 - 255) | |
Patient 3 | 98 | 100 | 44.5 | 2.8 (1 - 8) | 6.4 (4 - 11) | 1,300 (426 – 4,224) | |
Patient 4 | 49.4 | 44.7 | 8.4 | 10.7 (1 - 177) | 13.9 (2 - 84) | 9,900 (0.1 - 568 nM) | |
Patient 5 | 51.3 | 48.8 | 43.9 | 6.7 (1 - 36) | 7.1 (2 - 29) | 247.5 (89 - 688) |