. Author manuscript; available in PMC: 2015 May 1.

Published in final edited form as: Alcohol Clin Exp Res. 2014 Mar 21;38(5):1330–1338. doi: 10.1111/acer.12380

Table 3.

Relation of Prenatal Alcohol Exposure to Absolute Metabolite Concentrations in the Deep Cerebellar Nuclei

Metabolite	N	AA/day at time of conception		AA/day across pregnancy
		r	β	r	β
N-Acetylaspartate (NAA)	49	−0.33^*	−0.33^*	−0.26^†	−0.26^†
Glycerophosphocholine plus + Phosphocholine (Cho)	54	−0.23^†	−0.23^†	−0.37^**	−0.37^**
Creatine + Phosphocreatine (tCr)	51	0.01	0.01	−0.10	−0.10
Glutamate (Glu)	54	0.21^†	0.21^†	0.23^†	0.23^†
Glutamate + Glutamine (Glx)^a	54	0.35^**	0.32^*	0.38^**	0.35^**
Myo-Inositol (Ins)^b	51	−0.16	−0.13	−0.14	−0.13

AA = absolute alcohol; r represents the simple correlation between alcohol exposure and the metabolite; β is the standardized regression coefficient, after adjustment for the potential confounding variables listed below. Ns vary in the regression analyses due to missing cases for certain of the control variables.

Control variables: smoking during pregnancy

Control variables: child gender

^†

p < 0.10

p < 0.05

^**

p < 0.01