Table 2. CD69 in human diseases.

Disease	Cell Type	Tissue	References
Rheumatic diseases
Rheumatoid arthritis	T and NK cells	Synovial fluid	[22, 24, 27]
Osteoarthritis	T cells	Synovial membrane and fluid	[27]
Systemic sclerosis	Th17 and Treg cells	Peripheral blood	[29, 71]
Systemic lupus erythematosus	T, Treg and NK cells	Peripheral blood	[31, 63, 67]
Wegener’s granulomatosis	Th17 cells	Peripheral blood	[43]
Autoimmune diseases
Multiple sclerosis	Th17 cells	Cerebrospinal fluid	[35, 36]
Neuromyelitis optica	T cells	Peripheral blood	[37]
Autoimmune thyroiditis	T and Treg cells	Peripheral blood, thyroid gland	[40, 42]
Inflammatory diseases
Sarcoidosis	T cells	Peripheral blood, lung	[44]
Pneumonitis	CD4+ Tcells	Lung	[66]
Chronic bronchitis	CD4+ T cells	Peripheral blood, lung	[47]
Atherosclerosis	T cells	Blood vessels	[48]
Other diseases
Asthma	T cells, eosinophils	Peripheral blood, lung	[55, 56, 58]
Atopic dermatitis	Eosinophils	Peripheral blood	[57]
Hepatocellular carcinoma	Treg cell subset	Peripheral blood, liver	[64]
Kidney transplant	Treg cells	Peripheral blood, kidney	[52, 54]