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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: J Bone Miner Res. 2014 Mar;29(3):705–715. doi: 10.1002/jbmr.2064

Figure 5.

Figure 5

β-catenin heterozygous mice have decreased response to loading. Representative images of double fluorochrome labeling using calcein and alizarin red of loaded and non-loaded ulnae 3 mm distal to the midshaft region. Panel A: Male control and HET cKO mice. Panel B: Female control and HET cKO mice. Right top corner shows a magnification of similar regions to better visualize double labeling. Sections were viewed under fluorescent light to observe mineral deposition due to loading. Control females and males showed clear double labeling after loading; this response was absent in β-catenin heterozygous mice.