Table 2.
Parameter | Estimate | %BSV | 95%CI |
---|---|---|---|
CLstd (l/h/70 kg) | 3.52 | 46.6 | 1.35, 9.01 |
Vstd (l/70 kg) | 236 | 191 | 85.8, 497 |
Ftemp | 0.0934 | – | 0.0127, 0.244 |
FEAD | 0.558 | 2.6 | 0.329, 1.21 |
ErrADD (mcg/l) | 0.171 | ηRUV 0.643 | 0.0356, 0.657 |
ErrPROP (%) | 26 | 4.5, 48.9 |
BSV is the between-subject variability, CI is the confidence interval of the structural estimate; CLstd is the standardised clearance; Vstd is the standardised volume; additive and proportional error term respectively are ErrADD and ErrPROP.
FAED - acute energy depletion factor.