Fig. 1.

Effects of OFP-EA extract on serum ALT, AST and ALP in CCl₄-treated mice.

Mice were administrated CCl₄ dissolved in corn oil (2 ml/kg, 10% v/v) i.p. for 3 days for acute liver injury and orally for 7 weeks for chronic hepatic injury. Mice received silymarin (200 mg/kg) and OFP-EA extract (200 mg/kg each) before CCl₄ intoxication and the levels of ALT (a), AST (b) and ALP (c) are measured using commercial kits, respective. Data are expressed as mean±SEM of six observations. ^#P<0.05, compared with control treated group and *P<0.05, compared with CCl₄-treated group using one-way analysis of variance, followed by Dunnett's multiple range tests. OFP-EA: Olea europaea fruit pulp ethyl acetate extract, ALT: alanine aminotransferase, AST: aspartate aminotransferase, and ALP: alkaline phosphatase, □: acute liver injury,■: chronic liver injury.