Fig. 3.

Effects of OFP-EA extract on serum cholesterol profile.

Mice were administrated CCl₄ dissolved in corn oil i.p. for 3 days for acute liver injury and orally for 7 weeks for chronic hepatic injury. (a) Serum levels of total cholesterol, HDL and LDL/VLDL in acute liver injury. (b) Serum levels of total cholesterol, HDL and LDL/VLDL in chronic liver injury. (c) Serum levels of TG in acute and chronic liver injury. Mice received silymarin (200 mg/kg) and OFP-EA extract (200 mg/kg each) before CCl₄ treatment and the serum levels were measured using commercial kits, respectively. Data are expressed as mean±SEM of six observations. ^#P<0.05, compared with control treated group and *P<0.05, compared with CCl₄-treated group using one-way analysis of variance, followed by Dunnett's multiple range tests. grey colored bar: total cholesterol, grey checks bar: HDL, black checks bar: LDL/VLDL, □: acute liver injury, ■: chronic liver injury. OFP-EA: Olea europaea fruit pulp ethyl acetate extract, HDL: high-density lipoprotein, LDL/VLDL: low density/very lowdensity lipoprotein, TG: triglyceride.