Dregan 2014.

Study characteristics
Methods	Cluster RCT
Participants	Family practices within large research network, UK (Clinical Practice Research Datalink) 11 391 patients, 104 practices
Interventions	CDSS activated for patients on practice stroke register inviting physician to access prompts reminding them to adhere to guideline‐based secondary prevention (blood pressure control, recording strokes as hemorrhagic versus infarction, prescription of statins, and prescription of antiplatelet drugs)
Outcomes	Process adherence (prescribing), clinical endpoint (blood pressure and cholesterol targets)
Co‐Interventions	Education: Distribution of educational materials to providers in both control and intervention groups Beyond Clinician Education: None
CDSS Features ‐ Acknowledgement of CDSS Required	No
CDSS Features ‐ Other	Conveyed patient‐specific information, developed by study investigators, developed in consultation with users, included supporting information on‐screen, makes care recommendation, 'pull' mode of delivery, targeted underuse, user workflow considered in design
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment (selection bias)	Low risk
Incomplete outcome data (attrition bias) All outcomes	Low risk
Baseline characteristics similar?	Low risk
Unit of analysis error	Low risk