Judge 2006.

Study characteristics
Methods	Cluster RCT
Participants	Academically‐affiliated long‐term care facility, Canada 3843 episodes of care, 7 wards
Interventions	CDSS intended to improve medication safety at the time of order entry by flagging potential severe drug interactions, recent abnormal lab test results, requirement of special monitoring, dose reduction in elderly patients, or requirement of prophylactic measures
Outcomes	Process adherence (prescribing)
Co‐Interventions	Educational: None Beyond Clinician Education: None
CDSS Features ‐ Acknowledgement of CDSS Required	Yes ‐ required acknowledgement of the CDSS but not documentation of action taken
CDSS Features ‐ Other	Conveyed patient‐specific information, developed by study investigators, included supporting information on‐screen, interruptive, makes care recommendation, 'push' mode of delivery, targeted overuse, user workflow considered in design
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment (selection bias)	Low risk	N/A
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	N/A
Baseline characteristics similar?	Unclear risk	N/A
Unit of analysis error	High risk