Sequist 2011.

Study characteristics
Methods	Cluster RCT
Participants	Primary care practices affiliated with academic medical center, USA (Harvard Vanguard Medical Associates) 7083 patients, 292 providers, 15 health centers
Interventions	Two reminders that triggered when chief complaint of chest pain was coded in EHR during office visit (one recommended ECG and aspirin for high risk patients, a second recommended against cardiac stress testing for low risk patients)
Outcomes	Process adherence (prescribing, testing)
Co‐Interventions	Educational: None Beyond Clinician Education: None
CDSS Features ‐ Acknowledgement of CDSS Required	Yes ‐ required acknowledgement of the CDSS but not documentation of action taken
CDSS Features ‐ Other	Conveyed patient‐specific information, developed by study investigators, included supporting information on‐screen, interruptive, makes care recommendation, possible to execute desired action, 'push' mode of delivery, targeted overuse and underuse
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment (selection bias)	Low risk	N/A
Incomplete outcome data (attrition bias) All outcomes	Low risk
Baseline characteristics similar?	Low risk
Unit of analysis error	Low risk