Trial name or title	A multi-centre randomised controlled trial of Transfusion Indication Threshold Reduction on transfusion rates, morbidity and healthcare resources use following cardiac surgery
Methods	Multicentre randomised controlled trial
Participants	Patients aged 16 years and over undergoing cardiac surgery
Interventions	Liberal group - receive packed RBC if Hb concentration falls below 9 g/dL, objective is to maintain Hb above 9 g/dL Restrictive group - receive packed RBC if Hb concentration falls below 7.5 g/dL, objective is to maintain Hb above 7.5 g/dL
Outcomes	Infectious events, ischaemic events, units of RBC transfused, duration of hospital stay, all-cause mortality, resource use
Starting date	December 2008
Contact information
Notes

Hb = haemoglobin

RBC = red blood cells