Comparison 2. Ibuprofen 100 mg versus placebo.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Participants with at least 50% pain relief over 4 to 6 hours	4	396	Risk Ratio (M‐H, Fixed, 95% CI)	3.68 [2.29, 5.92]
2 Participants using rescue medication over 6 hours	3	296	Risk Ratio (M‐H, Fixed, 95% CI)	0.69 [0.57, 0.84]
3 Participants with any adverse event	3	310	Risk Ratio (M‐H, Fixed, 95% CI)	1.21 [0.71, 2.07]