De Miguel Rivero 1997.

Methods	RCT, DB, DD, single oral or intramuscular dose, 3 parallel groups Medication administered when baseline pain was of moderate to severe intensity Pain assessed at 0, 10, 20, 30, 45, 60, 90, 120 mins, then hourly up to 5 hours.
Participants	Total hip replacement N = 103 (106 randomised, 3 did not need medication) M = 47, F = 56 Mean age 62 years
Interventions	Ibuprofen arginine 400 mg, n = 36 Magnesic dipyrone, 2 g (IM), n = 33 Placebo, n = 34
Outcomes	PI: std 100 mm VAS PGE: std 5 point scale Numbers of participants using rescue medication Time to use of rescue medication Numbers with any adverse event Withdrawals
Notes	Oxford Quality Score: R1, DB2, W1 Rescue medication permitted after 1 hour.