Edwards 2002.

Methods	Five RCTs, DB, single oral dose, parallel groups Medication administered when baseline pain was of moderate to severe intensity Pain assessed at 0, 30, 60 mins, then hourly up to 8 hours.
Participants	Third molar extraction N = 339 M/F nor given Age not given
Interventions	Ibuprofen 400 mg, n = 338 Placebo, n = 339
Outcomes	PI: std 4 point scale PR: std 5 point scale PGE: std 5 point scale Numbers of participants using rescue medication Numbers with any adverse event Withdrawals
Notes	R2, DB2, W1 Rescue medication permitted ‐ no further details.