Gay 1996.
Methods | RCT, DB, single oral dose, 5 parallel groups Medication administered when baseline pain was of moderate to severe intensity Pain assessed at "regular intervals" up to 6 hours. |
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Participants | Third molar extraction N = 206 (204 analysed for efficacy) M = 86, F = 118 Mean age 24 years |
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Interventions | Ibuprofen 400 mg, n = 41 Dexketoprofen 5 mg, n = 41 Dexketoprofen 10 mg, n = 42 Dexketoprofen 20 mg, n = 41 Placebo, n = 39 |
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Outcomes | PI: std 4 point scale and 100 mm VAS PR: std 5 point scale PGE: std 5 point scale Numbers of participants using rescue medication Time to use of rescue medication Numbers with any adverse event Withdrawals |
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Notes | Oxford Quality Score: R1, DB2, W1 Rescue medication permitted after 1 hour. |