Hill 2001.
Methods | RCT, DB, single oral dose, 4 parallel groups Medication administered when baseline pain was of moderate to severe intensity Pain assessed at 0, 30, 60, mins, then hourly up to 12 hours. |
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Participants | Third molar extraction N = 198 M = 82, F = 116 Mean age 26 years |
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Interventions | Ibuprofen 400 mg, n = 49 Pregabalin 50 mg, n = 49 Pregabalin 300 mg, n = 50 Placebo, n = 50 |
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Outcomes | PI: std 4 point scale PR: std 5 point scale PGE: std 5 point scale Numbers of participants using rescue medication Time to use of rescue medication Numbers with any adverse event Withdrawals |
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Notes | Oxford Quality Score: R1, DB1, W1 Rescue medication permitted ‐ no further details |