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. 2009 Jul 8;2009(3):CD001548. doi: 10.1002/14651858.CD001548.pub2

Hill 2001.

Methods RCT, DB, single oral dose, 4 parallel groups
Medication administered when baseline pain was of moderate to severe intensity
Pain assessed at 0, 30, 60, mins, then hourly up to 12 hours.
Participants Third molar extraction
N = 198
M = 82, F = 116
Mean age 26 years
Interventions Ibuprofen 400 mg, n = 49
Pregabalin 50 mg, n = 49
Pregabalin 300 mg, n = 50
Placebo, n = 50
Outcomes PI: std 4 point scale
PR: std 5 point scale
PGE: std 5 point scale
Numbers of participants using rescue medication
Time to use of rescue medication
Numbers with any adverse event
Withdrawals
Notes Oxford Quality Score: R1, DB1, W1
Rescue medication permitted ‐ no further details