Laska 1986.

Methods	RCT, DB, single oral dose, 5 parallel groups Medication administered when baseline pain was of moderate to severe intensity Pain assessed at 0, 30, 60 mins, then hourly up to 6 hours.
Participants	Third molar extraction N = 200 (191 analysed for efficacy) M/F not given Mean age 23 years
Interventions	Ibuprofen 400 mg, n = 39 Ibuprofen 600 mg, n = 36 Ibuprofen 800 mg, n = 39 Aluminium ibuprofen 400 mg, n = 39 Placebo, n = 37
Outcomes	PI: std 4 point scale PR: std 5 point scale Numbers of participants using rescue medication Numbers with any adverse event Withdrawals
Notes	Oxford Quality Score: R1, DB2, W1 Rescue medication permitted after 1 hour.