Malmstrom 1999.

Methods	RCT, DB, single oral dose, 4 parallel groups Medication administered when baseline pain was of moderate to severe intensity Pain assessed at 0, 5, 10, 15, 20, 30, 45, 60, 90, 120 mins, then hourly up to 6 hours.
Participants	Third molar extraction N = 272 M = 100, F = 172 Mean age 23 years
Interventions	Ibuprofen 400 mg, n = 46 Rofecoxib 50 mg, n = 90 Celecoxib 200 mg, n = 91 Placebo, n = 45
Outcomes	PI: std 4 point scale PR: std 5 point scale PGE: std 5 point scale Numbers of participants using rescue medication Time to use of rescue medication Withdrawals
Notes	Oxford Quality Score: R2, DB2, W1 Rescue medication (paracetamol ±hydrocodone) permitted after 1.5 hours.